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pubmed:abstractText |
Acute lung injury (ALI) is a major cause of acute respiratory failure with high mortality despite lung-protective ventilation. Prior work has shown disordered inflammation and coagulation in ALI, with strong correlations between biomarker abnormalities and worse clinical outcomes. We measured plasma markers of inflammation, coagulation and fibrinolysis simultaneously to assess whether these markers remain predictive in the era of lung-protective ventilation.
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pubmed:affiliation |
Cardiovascular Research Institute, 505 Parnassus Avenue, University of California, San Francisco, San Francisco, CA 94143, USA. mcclintock.dana@gmail.com
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