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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-7-2
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pubmed:abstractText |
Type 1 diabetes is associated with a wide spectrum of susceptibility and protective genotypes within the HLA class II system. It has been reported that adults diagnosed with youth-onset type 1 diabetes more recently have been found to have fewer classical high-risk HLA class II genotypes than those diagnosed several decades ago. We hypothesized that such temporal trends in the distribution of HLA-DR, DQ genotypes would be evident, and perhaps even stronger, among 5- to 17-year-old Hispanic and non-Hispanic white (NHW) youth diagnosed with type 1 diabetes in Colorado between 1978 and 2004.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-10840992,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-11023146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-11508279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-12140742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-12687342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-1356957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-15465616,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-15530631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-1591322,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-17327312,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-1802481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-2351028,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-2784133,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-2912045,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-6402405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18356404-8137683
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1935-5548
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1392-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18356404-Adolescent,
pubmed-meshheading:18356404-Adult,
pubmed-meshheading:18356404-Child,
pubmed-meshheading:18356404-Child, Preschool,
pubmed-meshheading:18356404-Colorado,
pubmed-meshheading:18356404-Diabetes Mellitus, Type 1,
pubmed-meshheading:18356404-European Continental Ancestry Group,
pubmed-meshheading:18356404-Female,
pubmed-meshheading:18356404-Genetic Predisposition to Disease,
pubmed-meshheading:18356404-HLA Antigens,
pubmed-meshheading:18356404-HLA-DQ Antigens,
pubmed-meshheading:18356404-HLA-DQ beta-Chains,
pubmed-meshheading:18356404-HLA-DR Antigens,
pubmed-meshheading:18356404-HLA-DRB1 Chains,
pubmed-meshheading:18356404-Heterozygote Detection,
pubmed-meshheading:18356404-Hispanic Americans,
pubmed-meshheading:18356404-Histocompatibility Antigens Class II,
pubmed-meshheading:18356404-Humans,
pubmed-meshheading:18356404-Male,
pubmed-meshheading:18356404-Polymerase Chain Reaction,
pubmed-meshheading:18356404-Risk Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Trends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetes.
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pubmed:affiliation |
University of Colorado Denver, School of Medicine, Denver, Colorado, USA. kendra.vehik@uchsc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, N.I.H., Extramural
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