Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1992-1-9
|
| pubmed:abstractText |
In a Danish population-based non-Hodgkin lymphoma (NHL) registry, 1257 newly diagnosed NHL cases were registered over a 5-year period. Of these, 463 (37%) were extranodal. The gastrointestinal tract was the most common site of extranodal involvement (30% of the cases). Histologically, 44% of all extranodal NHL cases had high-grade, 17% intermediate and 27% low-grade features, while 12% were unclassified. The most common histological subtype (Kiel) was the centroblastic diffuse (23% of cases). 50% of all extranodal NHL were localised (stage IE or IIE) and 27% had B symptoms. Site-specific features included a strong age-correlation for thyroid and testes lymphoma (greater than 50 years) and a high prevalence of female cases in thyroid and salivary glands lymphomas (M/F 0.14 and 0.30, respectively). Overall 7-year survival for extranodal NHL was 46% (median 4.9 years). Poor prognosis patients could be identified by the presence of one or more of the following presentation characteristics: age greater than 65 years, B symptoms, high-grade histology, disseminated disease, elevated s-IgA and hyperuricaemia. Relative risk values ranged from 2.1 for age and B symptoms to 1.7 for hyperuricaemia.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0959-8049
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
27
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
1201-8
|
| pubmed:dateRevised |
2006-4-24
|
| pubmed:meshHeading |
pubmed-meshheading:1835586-Adolescent,
pubmed-meshheading:1835586-Adult,
pubmed-meshheading:1835586-Age Factors,
pubmed-meshheading:1835586-Aged,
pubmed-meshheading:1835586-Aged, 80 and over,
pubmed-meshheading:1835586-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1835586-Child,
pubmed-meshheading:1835586-Child, Preschool,
pubmed-meshheading:1835586-Cyclophosphamide,
pubmed-meshheading:1835586-Doxorubicin,
pubmed-meshheading:1835586-Female,
pubmed-meshheading:1835586-Humans,
pubmed-meshheading:1835586-Lymph Nodes,
pubmed-meshheading:1835586-Lymphoma, Non-Hodgkin,
pubmed-meshheading:1835586-Male,
pubmed-meshheading:1835586-Middle Aged,
pubmed-meshheading:1835586-Neoplasm Staging,
pubmed-meshheading:1835586-Prednisone,
pubmed-meshheading:1835586-Prognosis,
pubmed-meshheading:1835586-Risk Factors,
pubmed-meshheading:1835586-Sex Factors,
pubmed-meshheading:1835586-Vincristine
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Clinicopathological features and prognostic factors in extranodal non-Hodgkin lymphomas. Danish LYFO Study Group.
|
| pubmed:affiliation |
Department of Haematology, Odense University Hospital, Denmark.
|
| pubmed:publicationType |
Journal Article
|