pubmed:abstractText |
In past research, children with older siblings were more likely than others to wheeze at age 2 years, but less likely by age 6 years. Higher infection transmission and a down-regulated allergic immune response as a result of these infections, respectively, were suggested as the causes. However, in a study of children aged 0-3 years in a low-income urban community in New York City, USA, with high asthma prevalence, we observed no birth-order effect.
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pubmed:affiliation |
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA. mp2217@columbia.edu
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