Linked Life Data

18352751

Source:http://linkedlifedata.com/resource/pubmed/id/18352751

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2008-3-20
pubmed:abstractText
Recent advances in single molecule mechanics have made it possible to investigate the mechanical anisotropy of protein stability in great detail. A quantitative prediction of protein unfolding forces at experimental time scales has so far been difficult. Here, we present an elastically bonded network model to describe the mechanical unfolding forces of green fluorescent protein in eight different pulling directions. The combination of an elastic network and irreversible bond fracture kinetics offers a new concept to understand the determinants of mechanical protein stability.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0031-9007
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
100
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
098101
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Elastic bond network model for protein unfolding mechanics.
pubmed:affiliation
Dana-Farber Cancer Institute and BCMP, Harvard Medical School, Boston, MA 02115, USA. dietz@ph.tum.de
pubmed:publicationType
Journal Article