Linked Life Data

18352051

Source:http://linkedlifedata.com/resource/pubmed/id/18352051

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2 Pt 1
pubmed:dateCreated
2008-3-20
pubmed:abstractText
Lipid rafts, defined as domains rich in cholesterol and sphingolipids, are involved in many important plasma membrane functions. Recent studies suggest that the way cells handle membrane cholesterol is fundamental in the formation of such lateral heterogeneities. We propose to model the plasma membrane as a nonequilibrium phase-separating system where cholesterol is dynamically incorporated and released. The model shows how cellular regulation of membrane cholesterol may determine the nanoscale lipid organization when the lipid mixture is close to a phase separation boundary, providing a plausible mechanism for raft formation in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1539-3755
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
021907
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Actively maintained lipid nanodomains in biomembranes.
pubmed:affiliation
Departament de Química-Física, Universitat de Barcelona, Avda Diagonal 647, Barcelona, Spain.
pubmed:publicationType
Journal Article