Source:http://linkedlifedata.com/resource/pubmed/id/18351742
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2008-5-23
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pubmed:abstractText |
Two new acylated triterpenoid saponins were isolated from the branches of Schima noronhae by bioassay-guided purification. Their chemical structures were established on the basis of spectroscopic analysis and chemical means as 3-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-galactopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->2)]-beta-D-glucuronopyranosyl 22-O-angeloyl-A1-barrigenol (1) and 3-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-galactopyranosyl-(1-->3)-[beta-D-glucopyranosyl-(1-->2)]-beta-D-glucuronopyranosyl 22-O-angeloylerythrodiol (2). Compounds 1 and 2 showed cell growth inhibitory activity against both HeLa and DLD1 cells at a concentration of less than 10 microM.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
918-21
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pubmed:meshHeading |
pubmed-meshheading:18351742-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:18351742-Drug Screening Assays, Antitumor,
pubmed-meshheading:18351742-HeLa Cells,
pubmed-meshheading:18351742-Humans,
pubmed-meshheading:18351742-Molecular Structure,
pubmed-meshheading:18351742-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:18351742-Plants, Medicinal,
pubmed-meshheading:18351742-Saponins,
pubmed-meshheading:18351742-Thailand,
pubmed-meshheading:18351742-Theaceae,
pubmed-meshheading:18351742-Triterpenes
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pubmed:year |
2008
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pubmed:articleTitle |
Acylated triterpenoid saponins from Schima noronhae and their cell growth inhibitory activity.
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pubmed:affiliation |
Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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