Linked Life Data

1835122

Source:http://linkedlifedata.com/resource/pubmed/id/1835122

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1991-12-2
pubmed:abstractText
In order to study the effect of dietary n-3 fatty acids on osmotic fragility of human erythrocytes, 11 healthy subjects were given a supplement of 6 g day-1 of an oil containing 50% n-3 fatty acids for either 14 days or 34 days. Fourteen days after start the osmotic fragility was decreased by 60-80% (buffer-salt concentration 0.41%), and the level of n-3 fatty acids in membrane phospholipids was increased by approximately 60%. The decrease in fragility was less marked after 24 days and almost at the pre-supplementation level after 34 days. There was no correlation between changes in fragility and in the fatty acid pattern of membrane phospholipids of the erythrocytes. The changes induced in fatty acid composition of phospholipids did not affect membrane fluidity. It is concluded that factors other than the nature of fatty acids in membranes may be involved in modifying osmotic fragility, and that there is no correlation between membrane fragility and membrane fluidity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0036-5513
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
493-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
The decrease in osmotic fragility of erythrocytes during supplementation with n-3 fatty acids is a transient phenomenon.
pubmed:affiliation
Institute of Clinical Biochemistry, University of Oslo, Rikshospitalet, Norway.
pubmed:publicationType
Journal Article