Linked Life Data

18349696

Source:http://linkedlifedata.com/resource/pubmed/id/18349696

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-3-19
pubmed:abstractText
The serotonin transporter gene (SLC6A4) encodes a trans-membrane protein (5-HTT) that plays an important role in regulating serotonergic neurotransmission, which is known to be involved in many psychiatric disorders. A polymorphism in the transcriptional control region containing long (L) and short (S) variants (5-HTTLPR) as well as alleles of the variable number tandem repeats (VNTR) region were demonstrated. Higher serotonin levels among carriers of the S allele might exhibit increased liability of serotonin-mediated, psychopathology-like anxiety and depression and may impair social skills reflected by harm avoidance.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1473-5873
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-63
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Low level of harm avoidance is associated with serotonin transporter functional haplotype in alcohol-dependent individuals.
pubmed:affiliation
Department of addiction research/Clinic of Psychiatry/LMU Munich/Nussbaumstrasse 7/80336 Munich/Germany. gabi.koller@med.uni-muenchen.de
pubmed:publicationType
Journal Article, Comparative Study