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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2008-7-29
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pubmed:abstractText |
Mycosis fungoides (MF) is the most frequent cutaneous T-cell lymphoma (CTCL). Arsenic trioxide (As(2)O(3)) has recently been shown to be effective against leukemias, so we studied whether As(2)O(3) induces apoptosis of CTCL cells in vitro. We further investigated if As(2)O(3) is effective in a MF mouse model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Arsenicals,
http://linkedlifedata.com/resource/pubmed/chemical/Bax protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Bcl2l1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/Oxides,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2,
http://linkedlifedata.com/resource/pubmed/chemical/STAT5 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/arsenic trioxide,
http://linkedlifedata.com/resource/pubmed/chemical/bcl-2-Associated X Protein,
http://linkedlifedata.com/resource/pubmed/chemical/bcl-X Protein,
http://linkedlifedata.com/resource/pubmed/chemical/myeloid cell leukemia sequence 1...
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1569-8041
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1488-94
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pubmed:meshHeading |
pubmed-meshheading:18349030-Animals,
pubmed-meshheading:18349030-Antineoplastic Agents,
pubmed-meshheading:18349030-Apoptosis,
pubmed-meshheading:18349030-Arsenicals,
pubmed-meshheading:18349030-Cell Growth Processes,
pubmed-meshheading:18349030-Cell Line, Tumor,
pubmed-meshheading:18349030-Down-Regulation,
pubmed-meshheading:18349030-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18349030-Genes, bcl-2,
pubmed-meshheading:18349030-Humans,
pubmed-meshheading:18349030-Mice,
pubmed-meshheading:18349030-Mice, Nude,
pubmed-meshheading:18349030-Mycosis Fungoides,
pubmed-meshheading:18349030-NF-kappa B,
pubmed-meshheading:18349030-Oxides,
pubmed-meshheading:18349030-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:18349030-STAT5 Transcription Factor,
pubmed-meshheading:18349030-Skin Neoplasms,
pubmed-meshheading:18349030-T-Lymphocytes,
pubmed-meshheading:18349030-Xenograft Model Antitumor Assays,
pubmed-meshheading:18349030-bcl-2-Associated X Protein,
pubmed-meshheading:18349030-bcl-X Protein
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pubmed:year |
2008
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pubmed:articleTitle |
Arsenic trioxide down-regulates antiapoptotic genes and induces cell death in mycosis fungoides tumors in a mouse model.
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pubmed:affiliation |
Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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