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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-3-17
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pubmed:abstractText |
Several lines of evidence indicate a role for inflammatory processes in the development of cerebral aneurysms. Recently, polymorphisms in the promoter region of the interleukin 6 (IL6) gene were shown to be associated with intracranial aneurysmal disease. The purpose of this study was to verify the association of two functionally active polymorphisms (-174 G>C and -572 G>C) in the promoter region of the IL6 gene with the risk and clinical features of aneurysmal subarachnoid haemorrhage (SAH) in an Italian population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1468-330X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
471-3
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18344399-Adult,
pubmed-meshheading:18344399-Aged,
pubmed-meshheading:18344399-Female,
pubmed-meshheading:18344399-Gene Frequency,
pubmed-meshheading:18344399-Genetic Predisposition to Disease,
pubmed-meshheading:18344399-Genetics, Population,
pubmed-meshheading:18344399-Genotype,
pubmed-meshheading:18344399-Haplotypes,
pubmed-meshheading:18344399-Humans,
pubmed-meshheading:18344399-Interleukin-6,
pubmed-meshheading:18344399-Intracranial Aneurysm,
pubmed-meshheading:18344399-Italy,
pubmed-meshheading:18344399-Male,
pubmed-meshheading:18344399-Middle Aged,
pubmed-meshheading:18344399-Polymorphism, Genetic,
pubmed-meshheading:18344399-Promoter Regions, Genetic,
pubmed-meshheading:18344399-Risk Factors,
pubmed-meshheading:18344399-Subarachnoid Hemorrhage
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pubmed:year |
2008
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pubmed:articleTitle |
Interleukin 6 gene polymorphisms are not associated with aneurysmal subarachnoid haemorrhage in an Italian population.
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pubmed:affiliation |
Division of Neurosurgery, Department of Neuroscience, University of Turin, Via Cherasco 15-10126 Torino, Italy. marco.fontanella@unito.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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