GENERIC 18344027

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0027051, umls-concept:C0277785, umls-concept:C0475224, umls-concept:C1545588
pubmed:issue	2
pubmed:dateCreated	2008-3-17
pubmed:abstractText	One or several short cycles of ischemia/reperfusion before (preconditioning) or after (postconditioning) a sustained coronary occlusion with subsequent reperfusion reduce the ultimate infarct size. The protection is potent, but limited to a narrow time frame. In animal experiments, a complex signal transduction cascade was identified which results specifically in a reduction of reperfusion injury. There is evidence for both ischemic pre- and postconditioning in patients with coronary artery disease.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7801231
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0340-9937
pubmed:author	pubmed-author:HeuschGerdG, pubmed-author:SchulzRainerR, pubmed-author:SkyschallyAndreasA
pubmed:issnType	Print
pubmed:volume	33
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	88-100
pubmed:meshHeading	pubmed-meshheading:18344027-Animals, pubmed-meshheading:18344027-Apoptosis, pubmed-meshheading:18344027-Humans, pubmed-meshheading:18344027-Ischemic Preconditioning, Myocardial, pubmed-meshheading:18344027-Myocardial Infarction, pubmed-meshheading:18344027-Myocardial Reperfusion Injury, pubmed-meshheading:18344027-Myocardium, pubmed-meshheading:18344027-Signal Transduction
pubmed:year	2008
pubmed:articleTitle	Pathophysiology of myocardial infarction: protection by ischemic pre- and postconditioning.
pubmed:affiliation	Institute of Pathophysiology,West German Heart Center, UniversityHospital Essen, Germany.
pubmed:publicationType	Journal Article, Review, Research Support, Non-U.S. Gov't