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pubmed-article:18343108pubmed:abstractTextThe syntheses of a new class of barbiturate-based inhibitors for human and Escherichia Coli methionine aminopeptidase-1 (MetAP-1) are described. Some of the synthesized inhibitors show selective inhibition of the human enzyme with high potency.lld:pubmed
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pubmed-article:18343108pubmed:articleTitleSynthesis of barbiturate-based methionine aminopeptidase-1 inhibitors.lld:pubmed
pubmed-article:18343108pubmed:affiliationDepartment of Pharmaceutical Sciences, North Dakota State University, 1401 Albrecht Boulevard, Fargo, ND 58105, USA.lld:pubmed
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