Source:http://linkedlifedata.com/resource/pubmed/id/18341411
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3-4
|
| pubmed:dateCreated |
2008-3-17
|
| pubmed:abstractText |
Fetal tissue transplantation for Parkinson disease (PD) has demonstrated promising results in experimental and clinical studies. However, the widespread clinical application of this therapeutic approach is limited by a lack of fetal tissue. Human neural precursor cells (HNPCs) are attractive candidates for transplantation because of their long-term proliferation activity. Furthermore, these cells can be reproducibly expanded in a standardized fashion in suspension bioreactors. In this study the authors sought to determine whether the survival, differentiation, and migration of HNPCs after transplantation depended on the region of precursor cell origin, intracerebral site of transplantation, and duration of their expansion.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1092-0684
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
24
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
E8
|
| pubmed:meshHeading |
pubmed-meshheading:18341411-Amphetamine,
pubmed-meshheading:18341411-Animals,
pubmed-meshheading:18341411-Behavior, Animal,
pubmed-meshheading:18341411-Bioreactors,
pubmed-meshheading:18341411-Cell Differentiation,
pubmed-meshheading:18341411-Cell Movement,
pubmed-meshheading:18341411-Cell Survival,
pubmed-meshheading:18341411-Central Nervous System,
pubmed-meshheading:18341411-Central Nervous System Stimulants,
pubmed-meshheading:18341411-Disease Models, Animal,
pubmed-meshheading:18341411-Embryonic Stem Cells,
pubmed-meshheading:18341411-Female,
pubmed-meshheading:18341411-Fetus,
pubmed-meshheading:18341411-Humans,
pubmed-meshheading:18341411-Neurons,
pubmed-meshheading:18341411-Parkinson Disease,
pubmed-meshheading:18341411-Rats,
pubmed-meshheading:18341411-Rats, Wistar,
pubmed-meshheading:18341411-Stem Cell Transplantation
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Survival, differentiation, and migration of bioreactor-expanded human neural precursor cells in a model of Parkinson disease in rats.
|
| pubmed:affiliation |
Division of Neurosurgery, Department of Surgery, Cell Restoration Laboratory, Dalhousie Medical School, Halifax, Nova Scotia, Canada.
|
| pubmed:publicationType |
Journal Article
|