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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-6-24
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pubmed:databankReference |
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pubmed:abstractText |
The airways in patients with cystic fibrosis (CF) are characterized by the accumulation of tenacious, dehydrated mucus that is a precursor for chronic infection, inflammation, and tissue destruction. The clearance of mucus is an integral component of daily therapy. Inhaled mannitol is an osmotic agent that increases the water content of the airway surface liquid, and improves the clearance of mucus with the potential to improve lung function and respiratory health. To this end, this study examined the efficacy and safety of therapy with inhaled mannitol over a 2-week period.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0012-3692
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pubmed:author |
pubmed-author:AndersonSandra DSD,
pubmed-author:ByePeter T PPT,
pubmed-author:CharltonBrettB,
pubmed-author:CooperPeterP,
pubmed-author:DaviskasEvangeliaE,
pubmed-author:JaquesAnnaA,
pubmed-author:LesouëfPeter NPN,
pubmed-author:OlekKK,
pubmed-author:RobertsonColin FCF,
pubmed-author:ShadboltBruceB,
pubmed-author:StirlingRobert GRG,
pubmed-author:TurtonJames AJA
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pubmed:issnType |
Print
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pubmed:volume |
133
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1388-96
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pubmed:meshHeading |
pubmed-meshheading:18339790-Administration, Inhalation,
pubmed-meshheading:18339790-Adolescent,
pubmed-meshheading:18339790-Adult,
pubmed-meshheading:18339790-Child,
pubmed-meshheading:18339790-Confidence Intervals,
pubmed-meshheading:18339790-Cross-Over Studies,
pubmed-meshheading:18339790-Cystic Fibrosis,
pubmed-meshheading:18339790-Diuretics, Osmotic,
pubmed-meshheading:18339790-Double-Blind Method,
pubmed-meshheading:18339790-Female,
pubmed-meshheading:18339790-Humans,
pubmed-meshheading:18339790-Male,
pubmed-meshheading:18339790-Mannitol,
pubmed-meshheading:18339790-Middle Aged,
pubmed-meshheading:18339790-Quality of Life,
pubmed-meshheading:18339790-Questionnaires,
pubmed-meshheading:18339790-Respiratory Function Tests,
pubmed-meshheading:18339790-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Inhaled mannitol improves lung function in cystic fibrosis.
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pubmed:affiliation |
Department of Clinical Research, Pharmaxis Ltd, Frenchs Forest, NSW, Australia. anna.jaques@pharmaxis.com.au
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
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