Linked Life Data

18335344

Source:http://linkedlifedata.com/resource/pubmed/id/18335344

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2008-3-12
pubmed:abstractText
A new polyphenol, designated as salvianolic acid N, was isolated from the aqueous extracts of the roots of Salvia yunnanensis. Its chemical structure was elucidated as 3-(3,4-dihydroxylphenyl)-2-[(E)-3-(1,8,9-trihydroxyl-dibenzo[b,f]oxpin-3-yl)acryloxloxy]propanoic acid (1) on the basis of NMR and MS spectral analyses. The new polyphenol inhibited both HIV-1 IN in vitro and also reduced HIV-1 p24 antigen in MT-4 cell lines.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1028-6020
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
273-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:18335344-Anti-HIV Agents, pubmed-meshheading:18335344-Cell Line, pubmed-meshheading:18335344-Flavonoids, pubmed-meshheading:18335344-HIV Core Protein p24, pubmed-meshheading:18335344-HIV Integrase, pubmed-meshheading:18335344-HIV Integrase Inhibitors, pubmed-meshheading:18335344-HIV Reverse Transcriptase, pubmed-meshheading:18335344-HIV-1, pubmed-meshheading:18335344-Humans, pubmed-meshheading:18335344-Inhibitory Concentration 50, pubmed-meshheading:18335344-Nuclear Magnetic Resonance, Biomolecular, pubmed-meshheading:18335344-Optical Rotation, pubmed-meshheading:18335344-Phenols, pubmed-meshheading:18335344-Plant Roots, pubmed-meshheading:18335344-Polyphenols, pubmed-meshheading:18335344-Reverse Transcriptase Inhibitors, pubmed-meshheading:18335344-Salvia, pubmed-meshheading:18335344-Spectrometry, Mass, Electrospray Ionization, pubmed-meshheading:18335344-Spectrophotometry, Infrared, pubmed-meshheading:18335344-Spectrophotometry, Ultraviolet, pubmed-meshheading:18335344-Spectroscopy, Fourier Transform Infrared
pubmed:articleTitle
A potent anti-HIV polyphenol from Salvia yunnanensis.
pubmed:affiliation
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't