Linked Life Data

18334918

Source:http://linkedlifedata.com/resource/pubmed/id/18334918

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-3-12
pubmed:abstractText
Patients expressing the tacrolimus-metabolizing enzyme, cytochrome P450 (CYP) 3A5, require more tacrolimus to reach target concentrations. We studied the influence of the CYP3A5(*)3 allele, which results in the absence of CYP3A5 protein, on tacrolimus dose and exposure, as well as the incidence of biopsy-proven acute rejection (BPAR) after renal transplantation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1744-6872
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
339-48
pubmed:dateRevised
2008-5-15
pubmed:meshHeading
pubmed-meshheading:18334918-Acute Disease, pubmed-meshheading:18334918-Adrenal Cortex Hormones, pubmed-meshheading:18334918-Creatinine, pubmed-meshheading:18334918-Cytochrome P-450 CYP3A, pubmed-meshheading:18334918-Female, pubmed-meshheading:18334918-Genotype, pubmed-meshheading:18334918-Graft Rejection, pubmed-meshheading:18334918-Humans, pubmed-meshheading:18334918-Immunosuppressive Agents, pubmed-meshheading:18334918-International Agencies, pubmed-meshheading:18334918-Kidney Diseases, pubmed-meshheading:18334918-Kidney Transplantation, pubmed-meshheading:18334918-Male, pubmed-meshheading:18334918-Metabolic Clearance Rate, pubmed-meshheading:18334918-Middle Aged, pubmed-meshheading:18334918-Mycophenolic Acid, pubmed-meshheading:18334918-Prospective Studies, pubmed-meshheading:18334918-Risk Factors, pubmed-meshheading:18334918-Tacrolimus
pubmed:year
2008
pubmed:articleTitle
CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients.
pubmed:affiliation
Department of Internal Medicine, Renal Transplant Unit, Erasmus MC, Rotterdam, The Netherlands. d.a.hesselink@erasmusmc.nl
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study