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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-3-11
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pubmed:abstractText |
Idiopathic nephrotic syndrome in children is commonly associated with minimal change disease and response to steroid therapy. Steroid-unresponsive nephrotic syndrome is often characterized by persistent proteinuria and progression to chronic kidney disease. Focal segmental glomerulosclerosis is the leading cause of steroid-unresponsive nephrotic syndrome in childhood. There is no uniformed consensus as to the treatment of steroid-unresponsive nephrotic syndrome. Advances in the pathogenesis, genetics and biomarkers or surrogate markers may be useful for the diagnosis and identification of patients with steroid-unresponsive nephrotic syndrome, severity of disease, progression and response to therapy.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1040-8703
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-6
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pubmed:meshHeading |
pubmed-meshheading:18332710-Child,
pubmed-meshheading:18332710-Cyclosporins,
pubmed-meshheading:18332710-Glomerulosclerosis, Focal Segmental,
pubmed-meshheading:18332710-Humans,
pubmed-meshheading:18332710-Immunosuppressive Agents,
pubmed-meshheading:18332710-Mycophenolic Acid,
pubmed-meshheading:18332710-Nephrotic Syndrome,
pubmed-meshheading:18332710-Randomized Controlled Trials as Topic,
pubmed-meshheading:18332710-Sirolimus,
pubmed-meshheading:18332710-Tacrolimus,
pubmed-meshheading:18332710-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Evaluation and management of steroid-unresponsive nephrotic syndrome.
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pubmed:affiliation |
Division of Pediatric Nephrology, Children's Hospital at Montefiore, Bronx, New York 10467, USA. mdelrio@montefiore.org
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pubmed:publicationType |
Journal Article,
Review,
Research Support, N.I.H., Extramural
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