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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-10-22
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pubmed:abstractText |
We demonstrated brain perfusion abnormalities in a sibship with parkin-linked parkinsonism. The sibship consisted of a 64-year-old man and a 62-year-old woman. Both patients had homozygous deletions of exon 4 in the parkin gene. Hypoperfusion in the superior and middle frontal gyrus, and head of caudate nucleus was seen by SPECT with easy Z score imaging system in both patients. These findings may reflect their executive dysfunction demonstrated by neuropsychological tests.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1353-8020
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
581-3
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pubmed:meshHeading |
pubmed-meshheading:18331811-Brain,
pubmed-meshheading:18331811-Brain Mapping,
pubmed-meshheading:18331811-Exons,
pubmed-meshheading:18331811-Female,
pubmed-meshheading:18331811-Gene Deletion,
pubmed-meshheading:18331811-Humans,
pubmed-meshheading:18331811-Male,
pubmed-meshheading:18331811-Middle Aged,
pubmed-meshheading:18331811-Neuropsychological Tests,
pubmed-meshheading:18331811-Parkinsonian Disorders,
pubmed-meshheading:18331811-Siblings,
pubmed-meshheading:18331811-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:18331811-Ubiquitin-Protein Ligases
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pubmed:year |
2008
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pubmed:articleTitle |
Brain perfusion abnormalities in a sibship with parkin-linked parkinsonism.
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pubmed:affiliation |
Department of Neurology, Musashino Red Cross Hospital, 1-26-1 Kyonan-cho, Musashino-shi, Tokyo 180-8610, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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