rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1-3
|
pubmed:dateCreated |
2008-5-2
|
pubmed:abstractText |
Glutamate dysfunction has been implicated in the pathophysiology of schizophrenia. The metabotropic glutamate receptors (mGluRs) are G-protein-coupled receptors. GRM7, the gene that encodes mGluR7, is expressed in many regions of the human central nervous system. The GRM7 gene is located on human chromosome 3p26, which has been suggested by linkage analysis to contain a susceptibility locus for schizophrenia.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0920-9964
|
pubmed:author |
pubmed-author:AraiMakotoM,
pubmed-author:ArinamiTadaoT,
pubmed-author:HoriuchiYasueY,
pubmed-author:InadaToshiyaT,
pubmed-author:IritaniShyujiS,
pubmed-author:IshiguroHirokiH,
pubmed-author:ItokawaMasanariM,
pubmed-author:IwataNakaoN,
pubmed-author:KogaMinoriM,
pubmed-author:KunugiHiroshiH,
pubmed-author:NiizatoKazuhiroK,
pubmed-author:OhtsukiTsuyukaT,
pubmed-author:OzakiNorioN,
pubmed-author:SomeyaToshiukiT,
pubmed-author:UjikeHiroshiH,
pubmed-author:WatanabeYuichiroY
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pubmed:issnType |
Print
|
pubmed:volume |
101
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
9-16
|
pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:18329248-Adult,
pubmed-meshheading:18329248-Case-Control Studies,
pubmed-meshheading:18329248-Female,
pubmed-meshheading:18329248-Gene Frequency,
pubmed-meshheading:18329248-Genetic Predisposition to Disease,
pubmed-meshheading:18329248-Genotype,
pubmed-meshheading:18329248-Humans,
pubmed-meshheading:18329248-Male,
pubmed-meshheading:18329248-Middle Aged,
pubmed-meshheading:18329248-Polymorphism, Genetic,
pubmed-meshheading:18329248-Receptors, Metabotropic Glutamate,
pubmed-meshheading:18329248-Schizophrenia
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pubmed:year |
2008
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pubmed:articleTitle |
A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia.
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pubmed:affiliation |
Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|