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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-5-5
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pubmed:abstractText |
Animal and human studies have implicated an imbalance of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the pathogenesis of chronic obstructive pulmonary disease (COPD). MMP-9 protein is increased in COPD and we hypothesized that total MMP activity would be raised although this has not previously been measured.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0954-6111
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
845-51
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pubmed:meshHeading |
pubmed-meshheading:18328682-Adult,
pubmed-meshheading:18328682-Aged,
pubmed-meshheading:18328682-Aged, 80 and over,
pubmed-meshheading:18328682-Biological Markers,
pubmed-meshheading:18328682-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:18328682-Collagenases,
pubmed-meshheading:18328682-Female,
pubmed-meshheading:18328682-Forced Expiratory Volume,
pubmed-meshheading:18328682-Gelatinases,
pubmed-meshheading:18328682-Humans,
pubmed-meshheading:18328682-Male,
pubmed-meshheading:18328682-Matrix Metalloproteinase 9,
pubmed-meshheading:18328682-Matrix Metalloproteinases,
pubmed-meshheading:18328682-Middle Aged,
pubmed-meshheading:18328682-Pancreatic Elastase,
pubmed-meshheading:18328682-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:18328682-Sputum,
pubmed-meshheading:18328682-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:18328682-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:18328682-Vital Capacity
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pubmed:year |
2008
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pubmed:articleTitle |
MMP-9 protein level does not reflect overall MMP activity in the airways of patients with COPD.
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pubmed:affiliation |
Nottingham University Hospitals NHS Trust, Nottingham, UK.
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pubmed:publicationType |
Journal Article
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