| pubmed-article:18328559 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18328559 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:18328559 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:18328559 | lifeskim:mentions | umls-concept:C0205554 | lld:lifeskim |
| pubmed-article:18328559 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:18328559 | pubmed:dateCreated | 2008-5-16 | lld:pubmed |
| pubmed-article:18328559 | pubmed:abstractText | JAK2V617F is a common mutation in chronic myeloproliferative diseases (CMPDs). We have developed a system utilizing JAK2V617F-specific guanine quenching probe (QP-system) to detect JAK2V617F. With QP-system, results can be obtained from 100 microl of blood within 90 min. We compared QP-system with direct sequencing using 42 CMPD patients' specimens. JAK2V617F was detected in 25 specimens by QP-system, while direct sequencing failed to detect JAK2V617F in 7 of those 25. The presence of JAK2V617F mutation in these 7 specimens was confirmed by allele-specific PCR. These findings indicate that QP-system is more sensitive and useful than direct sequencing for diagnoses of CMPDs. | lld:pubmed |
| pubmed-article:18328559 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18328559 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18328559 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18328559 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18328559 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18328559 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18328559 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18328559 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:18328559 | pubmed:issn | 0145-2126 | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:KobayashiYuta... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:TakiTomohikoT | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:TaniwakiMasaf... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:KurodaJunyaJ | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:KimuraShinyaS | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:AshiharaEishi... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:IshikawaTakay... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:KawataEriE | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:KamitsujiYuri... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:MaekawaTairaT | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:YokotaAsumiA | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:StevensonWill... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:TakeuchiMikiM | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:HiraiMitsuhar... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:MurotaniYoshi... | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:TanakaRurikoR | lld:pubmed |
| pubmed-article:18328559 | pubmed:author | pubmed-author:MajimaSatoshi... | lld:pubmed |
| pubmed-article:18328559 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18328559 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:18328559 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18328559 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18328559 | pubmed:pagination | 1462-7 | lld:pubmed |
| pubmed-article:18328559 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:meshHeading | pubmed-meshheading:18328559... | lld:pubmed |
| pubmed-article:18328559 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18328559 | pubmed:articleTitle | Fully automated and super-rapid system for the detection of JAK2V617F mutation. | lld:pubmed |
| pubmed-article:18328559 | pubmed:affiliation | Department of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan. | lld:pubmed |
| pubmed-article:18328559 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18328559 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:3717 | entrezgene:pubmed | pubmed-article:18328559 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:18328559 | lld:entrezgene |
