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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0022131,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0079284,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0229525,
umls-concept:C0242184,
umls-concept:C0851285,
umls-concept:C2911684
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pubmed:issue |
2
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pubmed:dateCreated |
2008-3-10
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pubmed:abstractText |
The success of pancreatic islet transplantation depends largely on the capacity of the islet graft to survive the initial phase immediately after transplantation until revascularization is completed. Endothelin-1 (ET-1) is a strong vasoconstrictor which has been involved in solid organ graft failure but is also known to be a potent mitogenic/anti-apoptotic factor which could also potentially enhance the survival of the transplanted islets.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1590-8577
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-49
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18326921-Adult,
pubmed-meshheading:18326921-Aged,
pubmed-meshheading:18326921-Animals,
pubmed-meshheading:18326921-Anoxia,
pubmed-meshheading:18326921-Cell Line,
pubmed-meshheading:18326921-Endothelin-1,
pubmed-meshheading:18326921-Female,
pubmed-meshheading:18326921-Humans,
pubmed-meshheading:18326921-Immunohistochemistry,
pubmed-meshheading:18326921-Islets of Langerhans,
pubmed-meshheading:18326921-Islets of Langerhans Transplantation,
pubmed-meshheading:18326921-Male,
pubmed-meshheading:18326921-Middle Aged,
pubmed-meshheading:18326921-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:18326921-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:18326921-Phosphorylation,
pubmed-meshheading:18326921-RNA, Messenger,
pubmed-meshheading:18326921-Rats,
pubmed-meshheading:18326921-Rats, Inbred Lew,
pubmed-meshheading:18326921-Rats, Sprague-Dawley,
pubmed-meshheading:18326921-Receptor, Endothelin A,
pubmed-meshheading:18326921-Receptor, Endothelin B
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pubmed:year |
2008
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pubmed:articleTitle |
Expression and hypoxic regulation of the endothelin system in endocrine cells of human and rat pancreatic islets.
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pubmed:affiliation |
Clinic for Visceral and Transplant Surgery, Department of Surgery, Zurich University Hospital. Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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