Linked Life Data

18325664

Source:http://linkedlifedata.com/resource/pubmed/id/18325664

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pubmed-article:18325664pubmed:abstractTextWe describe a method for the measurement, analysis and display of cerebral cortical data obtained from coronal brain sections of the adult rat. In this method, regions-of-interest (ROI) are selected in the cortical mantle in a semiautomated fashion using a radial grid overlay, spaced in 15 degrees intervals from the midline. ROI measurements of intensity are mapped on a flattened two-dimensional surface. Topographic maps of statistical significance at each ROI allow for the rapid viewing of group differences. Cortical z-scores are displayed with the boundaries of brain regions defined according to a standard atlas of the rat brain. This method and accompanying software implementation (Matlab, Labview) allow for compact data display in a variety of autoradiographic and histologic studies of the structure and function of the rat brain.lld:pubmed
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pubmed-article:18325664pubmed:authorpubmed-author:ScreminO UOUlld:pubmed
pubmed-article:18325664pubmed:authorpubmed-author:HolschneiderD...lld:pubmed
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pubmed-article:18325664pubmed:dateRevised2011-4-21lld:pubmed
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pubmed-article:18325664pubmed:articleTitleFlattened cortical maps of cerebral function in the rat: a region-of-interest approach to data sampling, analysis and display.lld:pubmed
pubmed-article:18325664pubmed:affiliationDepartment of Psychiatry and the Behavioral Sciences, University of Southern California School of Medicine, Los Angeles, CA 90033, USA. holschne@usc.edulld:pubmed
pubmed-article:18325664pubmed:publicationTypeJournal Articlelld:pubmed
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