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rdf:type |
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lifeskim:mentions |
umls-concept:C0001613,
umls-concept:C0007776,
umls-concept:C0022655,
umls-concept:C0024779,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0228174,
umls-concept:C0449445,
umls-concept:C0542341,
umls-concept:C0870078,
umls-concept:C0870432,
umls-concept:C0936012,
umls-concept:C1511726,
umls-concept:C1555465,
umls-concept:C1705417
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pubmed:issue |
2
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pubmed:dateCreated |
2008-3-21
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pubmed:abstractText |
We describe a method for the measurement, analysis and display of cerebral cortical data obtained from coronal brain sections of the adult rat. In this method, regions-of-interest (ROI) are selected in the cortical mantle in a semiautomated fashion using a radial grid overlay, spaced in 15 degrees intervals from the midline. ROI measurements of intensity are mapped on a flattened two-dimensional surface. Topographic maps of statistical significance at each ROI allow for the rapid viewing of group differences. Cortical z-scores are displayed with the boundaries of brain regions defined according to a standard atlas of the rat brain. This method and accompanying software implementation (Matlab, Labview) allow for compact data display in a variety of autoradiographic and histologic studies of the structure and function of the rat brain.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0304-3940
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pubmed:author |
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|
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
434
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-84
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pubmed:dateRevised |
2011-4-21
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pubmed:meshHeading |
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pubmed:year |
2008
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pubmed:articleTitle |
Flattened cortical maps of cerebral function in the rat: a region-of-interest approach to data sampling, analysis and display.
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pubmed:affiliation |
Department of Psychiatry and the Behavioral Sciences, University of Southern California School of Medicine, Los Angeles, CA 90033, USA. holschne@usc.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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