Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-3-7
pubmed:abstractText
The Rho small guanosine triphosphatase Cdc42 is critical for diverse cellular functions, including regulation of actin organization, cell polarity, intracellular membrane trafficking, transcription, cell-cycle progression, and cell transformation. This implies that Cdc42 might be required for liver function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1528-0012
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
134
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
781-92
pubmed:meshHeading
pubmed-meshheading:18325391-Adaptor Proteins, Signal Transducing, pubmed-meshheading:18325391-Animals, pubmed-meshheading:18325391-Bile Ducts, pubmed-meshheading:18325391-Cadherins, pubmed-meshheading:18325391-Carcinoma, Hepatocellular, pubmed-meshheading:18325391-Cell Adhesion Molecules, pubmed-meshheading:18325391-Cell Polarity, pubmed-meshheading:18325391-Cell Proliferation, pubmed-meshheading:18325391-Cell Transformation, Neoplastic, pubmed-meshheading:18325391-Chronic Disease, pubmed-meshheading:18325391-Disease Progression, pubmed-meshheading:18325391-Hepatocytes, pubmed-meshheading:18325391-Hepatomegaly, pubmed-meshheading:18325391-Intercellular Junctions, pubmed-meshheading:18325391-Jaundice, Obstructive, pubmed-meshheading:18325391-Liver, pubmed-meshheading:18325391-Liver Neoplasms, pubmed-meshheading:18325391-Lung Neoplasms, pubmed-meshheading:18325391-Male, pubmed-meshheading:18325391-Mice, pubmed-meshheading:18325391-Mice, Inbred C57BL, pubmed-meshheading:18325391-Mice, Knockout, pubmed-meshheading:18325391-Organ Size, pubmed-meshheading:18325391-Precancerous Conditions, pubmed-meshheading:18325391-Protein Kinase C, pubmed-meshheading:18325391-Time Factors, pubmed-meshheading:18325391-cdc42 GTP-Binding Protein
pubmed:year
2008
pubmed:articleTitle
Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.
pubmed:affiliation
Molecular Cell Biology Unit, VIB, Ghent, Belgium; Department of Molecular Biology, Ghent University, Ghent, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't