The most common genetic change observed in adrenocortical carcinoma is loss of heterozygozity on chromosome 11q13. As genes on this chromosome may be important in the pathogenesis of adrenocortical carcinoma, we compared their expression profile between benign and malignant adrenocortical tissue.
Department of Surgery, University of California, San Francisco, School of Medicine, UCSF/Mt. Zion Medical Center, 1600 Divisadero Street, San Francisco, CA 94143-1674, USA.