Source:http://linkedlifedata.com/resource/pubmed/id/18321204
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2008-3-27
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pubmed:abstractText |
We report here a fatal case of nosocomial pneumonia due to a multidrug-resistant (MDR) strain of Enterobacter cloacae, which was also resistant to carbapenems, in a patient with a diagnosis of Churg-Strauss syndrome. The microorganism was investigated for the presence of metallo- and extended-spectrum beta-lactamases. The strain produced two class 1 integrons carrying bla(VIM-1) and aadA2 gene cassettes located on chromosomal and plasmidic DNA, respectively, and a plasmid-encoded SHV-12 extended-spectrum beta-lactamase. Our results clearly demonstrate the transfer of this kind of resistance in E. cloacae with potentially serious clinical implications.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1076-6294
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-7
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pubmed:meshHeading |
pubmed-meshheading:18321204-Bacterial Proteins,
pubmed-meshheading:18321204-Churg-Strauss Syndrome,
pubmed-meshheading:18321204-Cross Infection,
pubmed-meshheading:18321204-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:18321204-Enterobacter cloacae,
pubmed-meshheading:18321204-Enterobacteriaceae Infections,
pubmed-meshheading:18321204-Fatal Outcome,
pubmed-meshheading:18321204-Humans,
pubmed-meshheading:18321204-Integrons,
pubmed-meshheading:18321204-Male,
pubmed-meshheading:18321204-Middle Aged,
pubmed-meshheading:18321204-Pneumonia, Bacterial,
pubmed-meshheading:18321204-Polymerase Chain Reaction,
pubmed-meshheading:18321204-beta-Lactam Resistance,
pubmed-meshheading:18321204-beta-Lactamases
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pubmed:year |
2008
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pubmed:articleTitle |
Class I integron-borne bla(VIM-1) carbapenemase in a strain of Enterobacter cloacae responsible for a case of fatal pneumonia.
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pubmed:affiliation |
Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi dell'Aquila, L'Aquila, Italy.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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