|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007102,
umls-concept:C0013216,
umls-concept:C0016360,
umls-concept:C0079722,
umls-concept:C0549099,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1446409,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2008-3-4
|
|
pubmed:abstractText |
The major pathologic markers of prognosis in colorectal cancer include vascular invasion by tumor cells, invasion of adjacent lymph nodes, and perforation of the serosal wall. Recent work suggests that a high density of tumor-infiltrating lymphocytes (TIL) is associated with good outcome independently of these established prognostic markers. The aim of the present study was to investigate the prognostic significance of TILs and other routinely reported pathologic features in colon cancer, particularly in relation to the use of adjuvant chemotherapy.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1413-7
|
|
pubmed:meshHeading |
pubmed-meshheading:18316563-Adenocarcinoma, Mucinous,
pubmed-meshheading:18316563-Aged,
pubmed-meshheading:18316563-Antimetabolites, Antineoplastic,
pubmed-meshheading:18316563-Chemotherapy, Adjuvant,
pubmed-meshheading:18316563-Cohort Studies,
pubmed-meshheading:18316563-Colonic Neoplasms,
pubmed-meshheading:18316563-Female,
pubmed-meshheading:18316563-Fluorouracil,
pubmed-meshheading:18316563-Follow-Up Studies,
pubmed-meshheading:18316563-Humans,
pubmed-meshheading:18316563-Intestinal Perforation,
pubmed-meshheading:18316563-Lymphocytes, Tumor-Infiltrating,
pubmed-meshheading:18316563-Male,
pubmed-meshheading:18316563-Middle Aged,
pubmed-meshheading:18316563-Neoplasm Invasiveness,
pubmed-meshheading:18316563-Prognosis,
pubmed-meshheading:18316563-Retrospective Studies,
pubmed-meshheading:18316563-Survival Rate,
pubmed-meshheading:18316563-Treatment Outcome
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy.
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|
pubmed:affiliation |
School of Surgery and Pathology, University of Western Australia, Nedlands, Western Australia, Australia.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
