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rdf:type |
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lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0085862,
umls-concept:C0205263,
umls-concept:C0242184,
umls-concept:C1299583,
umls-concept:C1514474,
umls-concept:C1537846,
umls-concept:C1549571,
umls-concept:C1608386,
umls-concept:C2742945,
umls-concept:C2826015
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pubmed:issue |
5
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pubmed:dateCreated |
2008-3-4
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pubmed:abstractText |
MicroRNA (miRNA) expression alterations have been described in cancer. Many cancers are characterized by areas of hypoxia, enhanced hypoxia-inducible factor (HIF) levels, and increased expression of hypoxically regulated genes, all of which correlate with patient outcome. We examined hypoxia-induced miRNA expression changes to identify markers of survival in breast cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Basic Helix-Loop-Helix...,
http://linkedlifedata.com/resource/pubmed/chemical/HIF1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1, alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/MicroRNAs,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Von Hippel-Lindau Tumor Suppressor...,
http://linkedlifedata.com/resource/pubmed/chemical/endothelial PAS domain-containing...
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1078-0432
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1340-8
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pubmed:meshHeading |
pubmed-meshheading:18316553-Anoxia,
pubmed-meshheading:18316553-Basic Helix-Loop-Helix Transcription Factors,
pubmed-meshheading:18316553-Breast Neoplasms,
pubmed-meshheading:18316553-Cell Line, Tumor,
pubmed-meshheading:18316553-Female,
pubmed-meshheading:18316553-Follow-Up Studies,
pubmed-meshheading:18316553-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18316553-Humans,
pubmed-meshheading:18316553-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:18316553-MicroRNAs,
pubmed-meshheading:18316553-Middle Aged,
pubmed-meshheading:18316553-Prognosis,
pubmed-meshheading:18316553-RNA, Small Interfering,
pubmed-meshheading:18316553-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18316553-Transfection,
pubmed-meshheading:18316553-Tumor Cells, Cultured,
pubmed-meshheading:18316553-Tumor Markers, Biological,
pubmed-meshheading:18316553-Von Hippel-Lindau Tumor Suppressor Protein
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pubmed:year |
2008
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pubmed:articleTitle |
hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer.
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pubmed:affiliation |
Genomics Group, Wellcome Trust Centre for Human Genetics, The Henry Wellcome Building for Genomic Medicine, University of Oxford, Oxford, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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