Source:http://linkedlifedata.com/resource/pubmed/id/18316258
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2008-4-18
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pubmed:abstractText |
Most of the currently available anti-osteoporosis medications promptly and significantly influence the rate of bone turnover. Biochemical markers of bone turnover now provide a high sensitivity to change, allowing the detection of these bone turnover changes within a couple of weeks. Since the anti-fracture efficacy of inhibitors of bone resorption or stimulators of bone formation appears to be largely independent of baseline bone turnover, biochemical markers do not appear to play a significant role in the selection of one particular drug, for an individual patient. However, there are consistent data showing that short-term changes in biochemical markers of bone turnover may be significant predictors of future changes in bone mineral density or fracture reduction, hence suggesting that bone turnover markers play a significant role in the monitoring of anti-osteoporosis therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
8756-3282
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
832-6
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pubmed:meshHeading |
pubmed-meshheading:18316258-Biological Markers,
pubmed-meshheading:18316258-Bone Density,
pubmed-meshheading:18316258-Bone Density Conservation Agents,
pubmed-meshheading:18316258-Bone Remodeling,
pubmed-meshheading:18316258-Clinical Trials as Topic,
pubmed-meshheading:18316258-Female,
pubmed-meshheading:18316258-Humans,
pubmed-meshheading:18316258-Middle Aged,
pubmed-meshheading:18316258-Osteoporosis, Postmenopausal,
pubmed-meshheading:18316258-Prognosis
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pubmed:year |
2008
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pubmed:articleTitle |
Role of biochemical markers of bone turnover as prognostic indicator of successful osteoporosis therapy.
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pubmed:publicationType |
Editorial
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