Linked Life Data

18316166

Source:http://linkedlifedata.com/resource/pubmed/id/18316166

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2008-4-28
pubmed:abstractText
The transformation of head-movements into neural signals represents a multi-stage process. It depends on orientation and movement of the head, the geometry and mechanics of the vestibular sensors, and the ensuing processing of the peripheral vestibular signals. While this process is well understood for the semicircular canals, where each canal transduces the angular velocity in the corresponding canal plane, the contributions of the individual otoliths, our linear acceleration sensors, are still under debate. This is in part due to the complex geometrical structure of the otoliths. To improve our understanding of the otoliths, we have developed a new technique to visualize otolith function: using measured 3D-shapes of human otoliths and the observed 2D patterns of hair cell orientation over the epithelia, morphological polarization vectors are predicted. To visualize the geometric distribution of these vectors, we have created distribution plots which indicate the density of hair cell polarization vectors for the different directions. In many respects, our results closely agree with earlier recordings of polarization vectors of vestibular afferents in squirrel monkeys: for example, hair cells on the saccule do not cover the sagittal plane equally, but show a strong concentration in the dorso-ventral directions. Some discrepancies exist in the density distribution of otolith, which could provide valuable information for future anatomical investigations of the otoliths.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0378-5955
pubmed:author
pubmed:issnType
Print
pubmed:volume
239
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
12-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The distribution of otolith polarization vectors in mammals: comparison between model predictions and single cell recordings.
pubmed:affiliation
Department of Theoretical Astrophysics, University of Tübingen, Auf der Morgenstelle 10, 72076 Tübingen, Germany. rudijaeger@yahoo.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't