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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-3-4
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pubmed:abstractText |
CYP2C9 is a polymorphic enzyme that has been reported to metabolize several clinically useful drugs such as warfarin, phenytoin and non-steroidal anti-inflammatory drugs. We designed a rapid single-tube multiplex assay to detect four variant alleles of the CYP2C9 in a single polymerase chain reaction (PCR) and a single pyrosequencing reaction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2710
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-92
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pubmed:dateRevised |
2008-5-28
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pubmed:meshHeading |
pubmed-meshheading:18315785-Adult,
pubmed-meshheading:18315785-Aged,
pubmed-meshheading:18315785-Alleles,
pubmed-meshheading:18315785-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:18315785-Asian Continental Ancestry Group,
pubmed-meshheading:18315785-Female,
pubmed-meshheading:18315785-Genotype,
pubmed-meshheading:18315785-Humans,
pubmed-meshheading:18315785-Male,
pubmed-meshheading:18315785-Middle Aged,
pubmed-meshheading:18315785-Polymerase Chain Reaction,
pubmed-meshheading:18315785-Polymorphism, Genetic,
pubmed-meshheading:18315785-Sequence Analysis, DNA
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pubmed:year |
2008
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pubmed:articleTitle |
Development of a single-tube PCR-pyrosequencing method for the simultaneous and rapid detection of four variant alleles of CYP2C9 gene polymorphism.
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pubmed:affiliation |
Department of Clinical Pharmacology, Gunma University Graduate School of Medicine, Gunma, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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