Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-3-3
pubmed:abstractText
Cartilage has a limited capacity for self repair after injury. This biological deficiency has led to a variety of surgical attempts to improve the repair of injured articular cartilage surfaces over the past 50 years. The first example of clinical cartilage tissue engineering was performed in 1987 when a knee with an articular cartilage defect on the femoral condyle was treated by implanting the patient's own chondrocytes that had been expanded in vitro into the defect in combination with a covering mechanical membrane-the periosteum. This technology is either termed autologous chondrocyte transplantation (ACT) or autologous chondrocyte implantation (ACI). Today, many modifications of the technique exist, from the first generation to now second and third generations of chondrocyte implantation. This paper describes the basic techniques for the clinical use of chondrocyte implantation and gives an update on the clinical results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0020-1383
pubmed:author
pubmed:issnType
Print
pubmed:volume
39 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S40-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Autologous chondrocyte implantation--technique and long-term follow-up.
pubmed:affiliation
Department of Orthopaedics, Cartilage Research Unit, Göteborg University, Kungsbacka Hospital, Kungsbacka, Sweden. mats.brittberg@telia.com
pubmed:publicationType
Journal Article