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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-3-24
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pubmed:abstractText |
ADAMs are a gene family of multifunctional proteins. We undertook this study to determine which ADAM species is up-regulated in osteoarthritic (OA) cartilage and to examine its pathobiologic function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
778-89
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pubmed:meshHeading |
pubmed-meshheading:18311789-ADAM Proteins,
pubmed-meshheading:18311789-Aged,
pubmed-meshheading:18311789-Aged, 80 and over,
pubmed-meshheading:18311789-Cartilage, Articular,
pubmed-meshheading:18311789-Case-Control Studies,
pubmed-meshheading:18311789-Cell Proliferation,
pubmed-meshheading:18311789-Cells, Cultured,
pubmed-meshheading:18311789-Chondrocytes,
pubmed-meshheading:18311789-Cytokines,
pubmed-meshheading:18311789-Growth Substances,
pubmed-meshheading:18311789-Humans,
pubmed-meshheading:18311789-Insulin-Like Growth Factor Binding Protein 5,
pubmed-meshheading:18311789-Insulin-Like Growth Factor I,
pubmed-meshheading:18311789-Membrane Proteins,
pubmed-meshheading:18311789-Osteoarthritis, Knee,
pubmed-meshheading:18311789-RNA, Messenger,
pubmed-meshheading:18311789-Transforming Growth Factor beta
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pubmed:year |
2008
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pubmed:articleTitle |
ADAM-12 (meltrin alpha) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage.
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pubmed:affiliation |
School of Medicine, Keio University, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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