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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-3-3
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pubmed:abstractText |
We compare frequency-and time-domain formulations of deep-tissue fluorescence imaging of turbid media. Simulations are used to show that time-domain fluorescence tomography, implemented via the asymptotic lifetime-based approach, offers a significantly better separability of multiple lifetime targets than a frequency-domain approach. We also demonstrate experimentally, using complex-shaped phantoms, the advantages of the asymptotic time-domain approach over a Fourier-based approach for analyzing time-domain fluorescence data.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-10087617,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-12772999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-15084074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-15895582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-16292963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-16389827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-17632634,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-18040483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-19529654,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-19865337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18311295-9238055
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0146-9592
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
470-2
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:18311295-Computer Simulation,
pubmed-meshheading:18311295-Image Interpretation, Computer-Assisted,
pubmed-meshheading:18311295-Microscopy, Fluorescence,
pubmed-meshheading:18311295-Models, Biological,
pubmed-meshheading:18311295-Nephelometry and Turbidimetry,
pubmed-meshheading:18311295-Reproducibility of Results,
pubmed-meshheading:18311295-Sensitivity and Specificity,
pubmed-meshheading:18311295-Tomography
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pubmed:year |
2008
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pubmed:articleTitle |
Comparison of frequency-domain and time-domain fluorescence lifetime tomography.
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pubmed:affiliation |
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA. ankumar@nmr.mgh.harvard.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies,
Research Support, N.I.H., Extramural
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