|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
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|
pubmed:dateCreated |
2008-3-3
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|
pubmed:abstractText |
Pitavastatin is the first totally synthetic HMG-Co A reductase inhibitor in Japan that significantly reduces LDL cholesterol while raising HDL cholesterol. Clinical trial showed that pitavastatin has potent effects for LDL cholesterol lowering and is expected effectively to prevent atherosclerosis. To clarify the mechanism of reduction of atherosclerosis by pitavastatin, we examined the effect of pitavastatin on foam cell formation of RAW264.7 macrophages.
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pubmed:language |
jpn
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0031-6903
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
128
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
357-63
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|
pubmed:dateRevised |
2010-11-18
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|
pubmed:meshHeading |
pubmed-meshheading:18311054-Animals,
pubmed-meshheading:18311054-Cells, Cultured,
pubmed-meshheading:18311054-Cholesterol, HDL,
pubmed-meshheading:18311054-Cholesterol, LDL,
pubmed-meshheading:18311054-Foam Cells,
pubmed-meshheading:18311054-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:18311054-Mice,
pubmed-meshheading:18311054-Quinolines,
pubmed-meshheading:18311054-Sterol Esterase
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
[Effect of pitavastatin on macrophage cholesterol metabolism].
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|
pubmed:affiliation |
Department of Clinical Pharmacology, Graduate School of Chiba University, Chiba University Hospital, Japan.
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|
pubmed:publicationType |
Journal Article,
English Abstract,
Review
|
