Source:http://linkedlifedata.com/resource/pubmed/id/18308019
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2008-2-29
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pubmed:abstractText |
Hypertrophic cardiomyopathy and cardiac amyloidosis result in thickening of the left ventricle, as visualized by 2-dimensional echocardiography. Hemodynamically, hypertrophic cardiomyopathy can be typified by a left ventricular outflow tract gradient and systolic anterior motion of the mitral apparatus, findings rarely seen in cardiac amyloidosis. This case series reports 4 patients with cardiac light-chain amyloidosis and left ventricular outflow tract obstruction at rest, suggesting that there may be echocardiographic overlap between these 2 disparate disease processes. In a series of consecutive patients with cardiac light-chain amyloidosis over a 2-year period, the prevalence of these echocardiographic findings was approximately 4%. In conclusion, awareness of this overlap in echocardiographic presentation may permit more accurate diagnosis, particularly at early stages of amyloid disease, when more treatment options exist.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0002-9149
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
674-6
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pubmed:meshHeading |
pubmed-meshheading:18308019-Aged,
pubmed-meshheading:18308019-Amyloidosis,
pubmed-meshheading:18308019-Cardiomyopathy, Hypertrophic,
pubmed-meshheading:18308019-Diastole,
pubmed-meshheading:18308019-Echocardiography, Doppler,
pubmed-meshheading:18308019-Female,
pubmed-meshheading:18308019-Heart Diseases,
pubmed-meshheading:18308019-Heart Ventricles,
pubmed-meshheading:18308019-Humans,
pubmed-meshheading:18308019-Immunoglobulin Light Chains,
pubmed-meshheading:18308019-Male,
pubmed-meshheading:18308019-Middle Aged,
pubmed-meshheading:18308019-Rest,
pubmed-meshheading:18308019-Ventricular Dysfunction, Left,
pubmed-meshheading:18308019-Ventricular Outflow Obstruction
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pubmed:year |
2008
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pubmed:articleTitle |
Light-chain amyloidosis with echocardiographic features of hypertrophic cardiomyopathy.
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pubmed:affiliation |
Section of Cardiology, Department of Medicine, Boston Medical Center, Boston, MA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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