|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0078058,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0242184,
umls-concept:C0301625,
umls-concept:C0599894,
umls-concept:C1099354,
umls-concept:C1171892,
umls-concept:C2003941,
umls-concept:C2603343,
umls-concept:C2911684
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2008-2-29
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|
pubmed:abstractText |
To evaluate suppression efficiency of hypoxia inducible factor-1 alpha (HIF-1 alpha) specific siRNA derived from recombinant plasmid (pSUPER(H1-siHIF-1 alpha)) on both HIF-1 alpha mRNA and protein expression and concomitant downregulation of expression of downstream angiogenic factor vascular endothelial growth factor (VEGF).
|
|
pubmed:language |
chi
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0412-4081
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
43
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1028-35
|
|
pubmed:meshHeading |
pubmed-meshheading:18307948-Anoxia,
pubmed-meshheading:18307948-Cell Hypoxia,
pubmed-meshheading:18307948-Down-Regulation,
pubmed-meshheading:18307948-Genetic Vectors,
pubmed-meshheading:18307948-Humans,
pubmed-meshheading:18307948-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:18307948-RNA, Messenger,
pubmed-meshheading:18307948-RNA, Small Interfering,
pubmed-meshheading:18307948-Transfection,
pubmed-meshheading:18307948-Tumor Cells, Cultured,
pubmed-meshheading:18307948-Vascular Endothelial Growth Factor A
|
|
pubmed:year |
2007
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|
pubmed:articleTitle |
[Study on suppression of hypoxia inducible factor-1 alpha and vascular endothelial growth factor expression by siRNA targeting hypoxia inducible factor-1 alpha].
|
|
pubmed:affiliation |
Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China.
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|
pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|
