|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0013081,
umls-concept:C0035668,
umls-concept:C0078058,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0242184,
umls-concept:C0348080,
umls-concept:C0599894,
umls-concept:C1171892,
umls-concept:C2003941,
umls-concept:C2330894
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|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2008-2-29
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|
pubmed:abstractText |
To explore the effect of hypoxia inducible factor-1 alpha (HIF-1 alpha) gene on the expression of vascular endothelial growth factor (VEGF) in human retinal pigment epithelial (hRPE) cells under hypoxia conditions by using small hairpin loop RNA (shRNA) to silence HIF-1 alpha.
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pubmed:language |
chi
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0412-4081
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
43
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1022-7
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pubmed:meshHeading |
pubmed-meshheading:18307947-Cell Hypoxia,
pubmed-meshheading:18307947-Cells, Cultured,
pubmed-meshheading:18307947-Down-Regulation,
pubmed-meshheading:18307947-Gene Expression Regulation,
pubmed-meshheading:18307947-Gene Silencing,
pubmed-meshheading:18307947-Humans,
pubmed-meshheading:18307947-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:18307947-Pigment Epithelium of Eye,
pubmed-meshheading:18307947-RNA, Messenger,
pubmed-meshheading:18307947-RNA, Small Interfering,
pubmed-meshheading:18307947-Vascular Endothelial Growth Factor A
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
[Down-regulation of vascular endothelial growth factor in human retinal pigment epithelial cells by small hairpin loop RNA targeting hypoxia inducible factor-1 alpha under hypoxia condition].
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|
pubmed:affiliation |
Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. xqing163@21cn.com
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|
