18307737

Source:http://linkedlifedata.com/resource/pubmed/id/18307737

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0018787, umls-concept:C0020564, umls-concept:C0033414, umls-concept:C0205463
pubmed:issue	4
pubmed:dateCreated	2008-2-29
pubmed:abstractText	1. Heart failure rates have reached epidemic proportions in Western society. 2. New strategies proposed to improve cardiac function of the failing heart include regeneration, stem cell therapy, innovative methods for the revascularization of ischaemic cardiac tissue and the activation of signalling pathways that promote physiological growth (hypertrophy). 3. The insulin-like growth factor 1-phosphoinositide-3-kinase pathway is a well characterized regulator of physiological hypertrophy. 4. In this mini-review we present studies that suggest promoting physiological hypertrophy in the failing heart may be beneficial.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0425076
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1440-1681
pubmed:author	pubmed-author:JenningsGarry LGL, pubmed-author:McMullenJulie RJR, pubmed-author:OwenKate LKL, pubmed-author:PretoriusLynetteL
pubmed:issnType	Electronic
pubmed:volume	35
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	438-41
pubmed:meshHeading	pubmed-meshheading:18307737-Cardiomegaly, pubmed-meshheading:18307737-Exercise, pubmed-meshheading:18307737-Heart Failure, pubmed-meshheading:18307737-Humans
pubmed:year	2008
pubmed:articleTitle	Promoting physiological hypertrophy in the failing heart.
pubmed:affiliation	Baker Heart Research Institute, and Faculty of Medicine, Nursing and Health Sciences, Department of Medicine (Alfred Hospital), Monash University, Melbourne, Victoria, Australia.
pubmed:publicationType	Journal Article, Review, Research Support, Non-U.S. Gov't