The aim of this study was to determine the presence of the neuronal nitric oxide synthase (nNOS) in near full-term lambs with congenital diaphragmatic hernia (CDH) and its role in the modulation of pulmonary vascular basal tone.
Neuronal nitric oxide synthase does not contribute to the modulation of pulmonary vascular tone in fetal lambs with congenital diaphragmatic hernia (nNOS in CDH lambs).
Faculté de Médecine, Université Paris Descartes, EA 2511, Assistance Publique Hôpitaux de Paris, Service de Physiologie-Explorations Fonctionnelles, Hôpital Cochin, Paris, France. anthony.debuys-roessingh@chuv.ch