18303198

Source:http://linkedlifedata.com/resource/pubmed/id/18303198

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0022771, umls-concept:C0427965, umls-concept:C0445910, umls-concept:C1533691
pubmed:issue	1
pubmed:dateCreated	2008-2-27
pubmed:abstractText	Mycobacterium abscessus is the second most common etiology of pulmonary disease caused by nontuberculous mycobacteria in Korea. Although antimicrobial susceptibility tests are important for appropriate patient management in M. abscessus lung disease, the tests have never been investigated in Korea. Seventy-four isolates of M. abscessus recovered from patient respiratory samples were tested against eight antimicrobial agents following the guidelines set forth by the National Committee for Clinical Laboratory Standards. Of the parenteral antibiotics, amikacin (99%, 73/74) and cefoxitin (99%, 73/74) were active against most isolates. Imipenem (55%, 36/66) and tobramycin (36%, 27/74) had activity against moderate number of isolates. Of the oral antibiotics, clarithromycin (91%, 67/74) was active against the majority of isolates. Moxifloxacin (73%, 54/74) and ciprofloxacin (57%, 42/74) had activity against a moderate number of isolates. Doxycycline was the least active, inhibiting only 7% (5/74) of isolates. In conclusion, the variations in susceptibility within M. abscessus isolates to currently available antimicrobials suggest that the antimicrobial susceptibilities of any clinically significant M. abscessus isolate be needed individually.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-10921960, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-12370998, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-1317144, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-16361797, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-16361804, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-16478850, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-17277290, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-17409204, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-2069387, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-2327761, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-3875667, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-4083863, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-6353528, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-8484642, http://linkedlifedata.com/resource/pubmed/commentcorrection/18303198-9279284
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8703518
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	1011-8934
pubmed:author	pubmed-author:ChangChulhun LCL, pubmed-author:KimHojoongH, pubmed-author:KimShinokS, pubmed-author:KohWon-JungWJ, pubmed-author:KwonO JungOJ, pubmed-author:LewWoo JinWJ, pubmed-author:ParkEun MiEM, pubmed-author:ParkSunghoonS, pubmed-author:ParkYoung KilYK
pubmed:issnType	Print
pubmed:volume	23
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	49-52
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:18303198-Drug Resistance, Bacterial, pubmed-meshheading:18303198-Humans, pubmed-meshheading:18303198-Microbial Sensitivity Tests, pubmed-meshheading:18303198-Nontuberculous Mycobacteria
pubmed:year	2008
pubmed:articleTitle	In vitro antimicrobial susceptibility of Mycobacterium abscessus in Korea.
pubmed:affiliation	Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't