Source:http://linkedlifedata.com/resource/pubmed/id/18303161
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
2008-2-27
|
pubmed:abstractText |
This case report describes a 37-year-old man with a blind eye with opaque media. Histopathology revealed an aggressive adenocarcinoma of the retinal pigment epithelium with marked invasion of the choroid, retina, sclera and--not previously reported--the orbital and cranial optic nerve and subarachnoid space. The tumour seeded into the lumbar spinal-cord space. Metastatic foci--not in continuity with the primary process--developed in the parietal lobe and cerebellopontine angle. Adenocarcinoma of the retinal pigment epithelium, which occurs rarely in longstanding blind eyes, may exhibit aggressive behaviour with life-threatening risk of metastatic spread.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1468-2079
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
92
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
389-91
|
pubmed:dateRevised |
2009-2-27
|
pubmed:meshHeading |
pubmed-meshheading:18303161-Adenocarcinoma,
pubmed-meshheading:18303161-Adult,
pubmed-meshheading:18303161-Brain Neoplasms,
pubmed-meshheading:18303161-Down Syndrome,
pubmed-meshheading:18303161-Eye,
pubmed-meshheading:18303161-Fatal Outcome,
pubmed-meshheading:18303161-Humans,
pubmed-meshheading:18303161-Male,
pubmed-meshheading:18303161-Neoplasm Invasiveness,
pubmed-meshheading:18303161-Pigment Epithelium of Eye,
pubmed-meshheading:18303161-Retinal Neoplasms,
pubmed-meshheading:18303161-Spinal Cord Neoplasms
|
pubmed:year |
2008
|
pubmed:articleTitle |
Aggressive metastasising adenocarcinoma of the retinal pigment epithelium with trisomy 21.
|
pubmed:affiliation |
Department of Ophthalmology and Eye Hospital, University Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany. ludwig.heindl@augen.imed.uni-erlangen.de
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|