The risk of breast cancer associated with inheriting a BRCA1 mutation is extremely high, in addition, there is a 50% chance of transmitting this familial cancer mutation to any offspring.
Research Centre for Reproductive Health, Discipline of Obstetrics & Gynaecology, School of Paediatrics & Reproductive Health, University of Adelaide, Adelaide 5005, South Australia, Australia. melinda.jasper@adelaide.edu.au