rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1991-8-22
|
pubmed:abstractText |
We studied the endometrial structure and ultrastructure in serial biopsies from 16 patients with endometriosis treated with danazol (n = 9) or the combination cyproterone acetate plus ethinyl estradiol (n = 7) for 6 months. Biopsies were performed before and at 3 and 6 months of treatment. The material obtained was studied by light (LM), scanning (SEM) and transmission electron microscopy (TEM). A morphometric analysis was performed evaluating three morphometric and three stereologic indices. The results indicate that danazol had a progestational effect on endometrial glands and stroma, associated with a marked hypotrophy of the mucosa. The cyproterone acetate/ethinyl estradiol combination induced progressive atrophy of the endometrium with an increase in the stromal component and a reduction of glandular tissue.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0301-2115
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
40
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
137-43
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1830018-Adult,
pubmed-meshheading:1830018-Biopsy,
pubmed-meshheading:1830018-Cyproterone,
pubmed-meshheading:1830018-Cyproterone Acetate,
pubmed-meshheading:1830018-Danazol,
pubmed-meshheading:1830018-Drug Combinations,
pubmed-meshheading:1830018-Endometriosis,
pubmed-meshheading:1830018-Endometrium,
pubmed-meshheading:1830018-Estradiol,
pubmed-meshheading:1830018-Ethinyl Estradiol,
pubmed-meshheading:1830018-Female,
pubmed-meshheading:1830018-Follicle Stimulating Hormone,
pubmed-meshheading:1830018-Humans,
pubmed-meshheading:1830018-Luteinizing Hormone
|
pubmed:year |
1991
|
pubmed:articleTitle |
Endometrial patterns during danazol and cyproterone acetate treatment for endometriosis: structural and ultrastructural study.
|
pubmed:affiliation |
1st Department of Obstetrics and Gynecology, University of Milan, Italy.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|