18299945

Source:http://linkedlifedata.com/resource/pubmed/id/18299945

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0030274, umls-concept:C0205207, umls-concept:C0221198, umls-concept:C0227579, umls-concept:C0333348, umls-concept:C0439810, umls-concept:C0728939, umls-concept:C0728940, umls-concept:C1709160
pubmed:issue	6
pubmed:dateCreated	2008-5-6
pubmed:abstractText	INTRODUCTION: For treatment of inflammatory and benign neoplastic lesions of the pancreatic head, a subtotal or total pancreatic head resection is a limited surgical procedure with the impact of replacing the application of a Whipple procedure. The objective of this work is to describe the technical modifications of subtotal and total pancreatic head resection for inflammatory and neoplastic lesions of the pancreas. The advantages of this limited surgical procedure are the preservation of the stomach, the duodenum and the extrahepatic biliary ducts for treatment of benign lesions of the pancreatic head, papilla, and intrapancreatic segment of the common bile duct. For chronic pancreatitis with an inflammatory mass complicated by compression of the common bile duct or causing multiple pancreatic main duct stenoses and dilatations, a subtotal pancreatic head resection results in a long-lasting pain control. Performing, in addition, a biliary anastomosis or a Partington Rochelle type of pancreatic main duct drainage, respectively, is a logic and simple extension of the procedure. The rationale for the application of duodenum-preserving total pancreatic head resection for cystic neoplastic lesions are complete exstirpation of the tumor and, as a consequence, interruption of carcinogenesis of the neoplasia preventing development of pancreatic cancer. Duodenum-preserving total head resection necessitates additional biliary and duodenal anastomoses. For mono-centric IPMN, MCN, and SCA tumors, located in the pancreatic head, total duodenum-preserving pancreatic head resection can be performed without hospital mortality and resurgery for recurrency. Based on controlled clinical trials, duodenum-preserving pancreatic head resection is superior to the Whipple-type resection with regard to lower postoperative morbidity, almost no delay of gastric emptying, preservation of the endocrine function, lower frequency of rehospitalization, early professional rehabilitation, and establishment of a predisease level of quality of life. CONCLUSION: The limited surgical procedures of subtotal or total pancreatic head resection are simple, safe, ensures free tumour margins and replace in the authors institution the application of a Whipple-type head resection.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9706084
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1091-255X
pubmed:author	pubmed-author:BegerH GHG, pubmed-author:GansaugeFF, pubmed-author:PochBB, pubmed-author:RayB ABA
pubmed:issnType	Print
pubmed:volume	12
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1127-32
pubmed:meshHeading	pubmed-meshheading:18299945-Humans, pubmed-meshheading:18299945-Pancreatic Cyst, pubmed-meshheading:18299945-Pancreaticoduodenectomy, pubmed-meshheading:18299945-Pancreatitis, pubmed-meshheading:18299945-Treatment Outcome
pubmed:year	2008
pubmed:articleTitle	Duodenum-preserving subtotal and total pancreatic head resections for inflammatory and cystic neoplastic lesions of the pancreas.
pubmed:affiliation	Department of General and Visceral Surgery, University of Ulm (-9/2001), Ulm, Germany. hans.beger@uniklinik-ulm.de
pubmed:publicationType	Journal Article, Review