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rdf:type |
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lifeskim:mentions |
umls-concept:C0003241,
umls-concept:C0010806,
umls-concept:C0011906,
umls-concept:C0021966,
umls-concept:C0037473,
umls-concept:C0205195,
umls-concept:C0245382,
umls-concept:C0549473,
umls-concept:C0598849,
umls-concept:C0752063,
umls-concept:C1552644,
umls-concept:C1823153,
umls-concept:C2349976
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pubmed:issue |
3
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pubmed:dateCreated |
2008-2-26
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pubmed:abstractText |
The microscopic distinction between benign and malignant thyroid lesions in clinical practice is still largely based on conventional histology. This study was performed to evaluate the diagnostic value of galectin-3 (Gal-3), Hector Battifora mesothelial-1 (HBME-1), cytokeratin (CK)-19, CBP P300-interacting transactivator with glutamic acid E- and aspartic acid D-rich C-terminal domain (CITED-1), fibronectin (FN)-1, peroxisome proliferator-activated receptor (PPAR)-gamma, and intracellular sodium/iodide symporter (iNIS) immunostaining in a large panel of thyroid neoplasms. Our study differed from earlier ones with regard to the identification of optimal semiquantitative cut-off levels using receiver operator curve (ROC) analysis and hierarchical cluster analysis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/CITED1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fibronectins,
http://linkedlifedata.com/resource/pubmed/chemical/Galectin 3,
http://linkedlifedata.com/resource/pubmed/chemical/HBME-1 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Keratin-19,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PPAR gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Symporters,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/sodium-iodide symporter
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1479-683X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
158
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
375-84
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pubmed:meshHeading |
pubmed-meshheading:18299472-Adenocarcinoma, Follicular,
pubmed-meshheading:18299472-Antibodies,
pubmed-meshheading:18299472-Carcinoma, Papillary,
pubmed-meshheading:18299472-Diagnosis, Differential,
pubmed-meshheading:18299472-Fibronectins,
pubmed-meshheading:18299472-Galectin 3,
pubmed-meshheading:18299472-Goiter, Nodular,
pubmed-meshheading:18299472-Graves Disease,
pubmed-meshheading:18299472-Humans,
pubmed-meshheading:18299472-Immunohistochemistry,
pubmed-meshheading:18299472-Keratin-19,
pubmed-meshheading:18299472-Nuclear Proteins,
pubmed-meshheading:18299472-PPAR gamma,
pubmed-meshheading:18299472-ROC Curve,
pubmed-meshheading:18299472-Symporters,
pubmed-meshheading:18299472-Thyroid Neoplasms,
pubmed-meshheading:18299472-Transcription Factors,
pubmed-meshheading:18299472-Tumor Markers, Biological
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pubmed:year |
2008
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pubmed:articleTitle |
Combined immunostaining with galectin-3, fibronectin-1, CITED-1, Hector Battifora mesothelial-1, cytokeratin-19, peroxisome proliferator-activated receptor-{gamma}, and sodium/iodide symporter antibodies for the differential diagnosis of non-medullary thyroid carcinoma.
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pubmed:affiliation |
Department of Endocrinology, C4-R, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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