|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2008-7-30
|
|
pubmed:abstractText |
Oral submucous fibrosis (OSF) is a chronic fibrotic disease of oral mucosa and oropharynx, induced by betel quid chewing often resulting in restricted mouth opening. The principal cells implicated as a source of extracellular matrix in areas of fibrosis are fibroblasts. Accumulation of connective tissue matrix is secondary to factors such as cytokines and growth factors. The contribution of basic fibroblast growth factor (bFGF) in disease progression and the consequent stromal changes with increase in the severity of OSF was studied.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
D
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
1600-0714
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
37
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
402-11
|
|
pubmed:meshHeading |
pubmed-meshheading:18298475-Adult,
pubmed-meshheading:18298475-Case-Control Studies,
pubmed-meshheading:18298475-Endothelial Cells,
pubmed-meshheading:18298475-Extracellular Matrix,
pubmed-meshheading:18298475-Female,
pubmed-meshheading:18298475-Fibroblast Growth Factor 2,
pubmed-meshheading:18298475-Fibroblasts,
pubmed-meshheading:18298475-Humans,
pubmed-meshheading:18298475-Immunohistochemistry,
pubmed-meshheading:18298475-Male,
pubmed-meshheading:18298475-Middle Aged,
pubmed-meshheading:18298475-Oral Submucous Fibrosis,
pubmed-meshheading:18298475-Reference Values,
pubmed-meshheading:18298475-Severity of Illness Index,
pubmed-meshheading:18298475-Tissue Distribution
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
The role of basic fibroblast growth factor in oral submucous fibrosis pathogenesis.
|
|
pubmed:affiliation |
Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal, Karnataka, India.
|
|
pubmed:publicationType |
Journal Article
|
