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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-8-1
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pubmed:abstractText |
The administration of indomethacin as a prophylactic against heterotopic ossification following the implantation of total hip-joint endoprosteses entails the risk of gastrointestinal side-effects. A prospective randomized study set out to determine the effectiveness of ranitidine and sucralfate as a secondary treatment for the protection of the stomach. Comparison with a placebo group monitored at the same time confirmed the efficacy of both medicaments. Both ranitidine (2 x 150 mg) and sucralfate (4 x 1 g) were able to prevent the occurrence of ulcers of the mucous membrane of both stomach and duodenum. Thanks to postoperative prophylactic treatment with indomethacin (2 x 50 mg for 3 weeks), there were no serious ossifications (degree II or III according to Arqu).
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0044-3220
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
178-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1829300-Adult,
pubmed-meshheading:1829300-Aged,
pubmed-meshheading:1829300-Aged, 80 and over,
pubmed-meshheading:1829300-Dose-Response Relationship, Drug,
pubmed-meshheading:1829300-Female,
pubmed-meshheading:1829300-Gastric Mucosa,
pubmed-meshheading:1829300-Gastroscopy,
pubmed-meshheading:1829300-Hip Prosthesis,
pubmed-meshheading:1829300-Humans,
pubmed-meshheading:1829300-Indomethacin,
pubmed-meshheading:1829300-Male,
pubmed-meshheading:1829300-Middle Aged,
pubmed-meshheading:1829300-Ossification, Heterotopic,
pubmed-meshheading:1829300-Postoperative Complications,
pubmed-meshheading:1829300-Ranitidine,
pubmed-meshheading:1829300-Sucralfate
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pubmed:articleTitle |
[Prevention of ossification after total hip endoprosthesis with indomethacin and its effect on gastric mucosa].
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pubmed:affiliation |
Allgem. Orthop. Abteilung, Orthopädisches Krankenhaus Wien-Gersthof.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Randomized Controlled Trial
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